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【剑桥大学最新研究】全自动探头监护系统-TBI患者采用经颅多普勒获得最优脑灌注...

发布日期【2018-10-11】 已浏览【】次

Individualized cerebral perfusion pressure (CPP) targets may be derived via assessing the minimum of the parabolic relationship
between an index of cerebrovascular reactivity and CPP. This minimum is termed the optimal CPP (CPPopt), and literature
suggests that the further away CPP is from CPPopt, the worse is clinical outcome in adult traumatic brain injury (TBI). Typically,
CPPopt estimation is based on intracranial pressure (ICP)-derived cerebrovascular reactivity indices, given ICP is commonly
measured and provides continuous long duration data streams. The goal of this study is to describe for the first time the
application of robotic transcranial Doppler (TCD) and the feasibility of determining CPPopt based on TCD autoregulation
indices